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Adaptol instructions for use, contraindications, side effects, reviews. Medicine Adaptol: an ambulance for the nervous system Is it possible to drink Adaptol at night

Active substance : mebicar
Each tablet contains 300 mg mebicar.
Excipients : methylcellulose, calcium stearate.

Pharmacotherapeutic group

Other anxiolytics.
ATX code: N05BX.

Pharmacological properties

Pharmacodynamics
The active substance of the drug Adaptol is close in chemical structure to the natural metabolites of the body - its molecule consists of two methylated urea fragments that are part of the bicyclic structure. Let's easily dissolve in water and in many organic solvents. Adaptol is chemically inert, does not interact with acids, alkalis, oxidizing and reducing agents, various drugs and food components. Adaptol acts on the activity of structures included in the limbic-reticular complex, in particular, on the emotiogenic zones of the hypothalamus, and also has an effect on all 4 major neurotransmitter systems - GABA, choline, serotonin and adrenergic, but does not have a peripheral adrenonegative effect. Adaptol eliminates or reduces anxiety, anxiety, fear, internal emotional stress and irritability. The calming effect of the drug is not accompanied by muscle relaxation and impaired coordination of movements. The drug does not reduce mental and motor activity, so Adaptol can be used during the working day or study. The drug does not create high spirits, a feeling of euphoria. It does not have a hypnotic effect, but enhances the effect of hypnotics and improves the course of sleep in case of its disturbances.
Pharmacokinetics
The active substance of the drug Adaptol is well (77-80%) absorbed from the gastrointestinal tract, up to 40% of the dose taken is bound by erythrocytes. The rest does not bind to plasma proteins and is in the plasma in a free form, so the active substance is freely distributed throughout the body and freely overcomes cell membranes. The maximum concentration of the active substance in the blood is reached 0.5 hours after taking the drug and the high level persists for 3-4 hours, then gradually decreases. 55-70% of the dose taken is excreted from the body with urine, the rest - with feces unchanged during the day.
The active substance of the drug is not metabolized and does not accumulate in the body.

Indications for use

Somatoform dysfunction of the autonomic nervous system and other neurotic disorders.

Dosage and administration

Adaptol is taken orally, regardless of the meal.
adults take 300-600 mg 2-3 times a day.
The maximum single dose is 3 g, the highest daily dose is 10 g.
The duration of the treatment course is from several days to 2-3 months.
Elderly patients do not need to reduce the dose.
Patients with liver failure dose reduction is not required.
At patients with renal insufficiency dose adjustment has not been studied. In these patients, the drug should be administered with caution.
Data on the safety and efficacy of Adaptol in children and adolescents under the age of 18 missing.

Side effects

Adaptol, like all medicines, can cause side effects that may not affect everyone.
The frequency of side effects according to the MedDRA classification system (Medical Dictionary of Regulatory Terminology):
Very common (≥1/10);
Frequent (≥1/100 to<1/10);
Uncommon (≥1/1000 to<1/100);
Rare (≥1/10,000 to<1/1000);
very rare (<1/10 000);
Unknown (cannot be determined from available data).
Immune System Disorders: unknown - hypersensitivity (hypersensitivity).
Nervous System Disorders: rare - dizziness; unknown - headache.
Cardiovascular disorders: rare - lowering blood pressure.
Gastrointestinal disorders: rare - dyspeptic disorders (expressed as a feeling of bitterness in the mouth, nausea, vomiting, abdominal pain, diarrhea).
Skin and subcutaneous tissue disorders: allergic reactions (angioedema, swelling of the eyelids, swelling of the face, swelling of the lips, swelling of the tongue, rash, papular rash, itching, erythema, urticaria, swelling of the skin), hyperhidrosis.
In the event of an allergic reaction, the drug should be discontinued.
Respiratory, thoracic and mediastinal disorders: unknown - bronchospastic reactions, an attack of bronchospasm. .
H kidney and urinary tract disorders: unknown - polyuria, nocturia (frequent urination at night).
General disorders: rare - decrease in body temperature, weakness; unknown - chest pain, swelling of the extremities, localized edema.
Metabolic and nutritional disorders: unknown - loss of appetite.
A decrease in blood pressure and / or a decrease in body temperature (body temperature may drop by 1-1.5 ° C) is not a reason for discontinuing the drug. Blood pressure and body temperature return to normal after the end of the course of treatment.
In the event of adverse reactions, including those not listed in this leaflet, you must stop taking the drug and consult a doctor.

Contraindications

Hypersensitivity to the active substance or to excipients of the drug.

Overdose

The drug is of low toxicity. Two reports of cases of overdose have been received. A single dose of the drug in a suicide attempt at a dose of 30 g did not lead to the development of a lethal outcome.
Treatment: in case of overdose, conventional detoxification methods are carried out, including gastric lavage, and symptomatic therapy.
The specific antidote is not known.

Precautionary measures

Isolated reports of cases of acute hypersensitivity reactions (hypersensitivity) have been received.

The use of the drug during pregnancy and lactation

The active substance penetrates well into all tissues and body fluids. Adequately controlled clinical studies of the use of the drug during pregnancy and lactation are not available, so prescribing the drug is not recommended.

Adaptol is an anxiolytic agent. It is a daytime tranquilizer that has a sedative effect and reduces anxiety. Adaptol does not cause drowsiness or any other sedative effects, so it can be taken during the working day. The drug also has a nootropic effect. This is manifested in the improvement of brain activity and the coherence of thinking.

Release form

Adaptol is available in the form of white round flat-cylindrical tablets with a score and a chamfer.

Composition of Adaptol

Adaptol contains:

  • Tetra(500 mg);
  • Methylcellulose (3.3 mg);
  • Calcium stearate (1.7 mg).

Analogues

The drugs included in the same pharmacological group with Adaptol include:

  • Atarax;
  • Afobazole;
  • diazepam;
  • Zolomax;
  • Xanax;
  • Relanium.

The same active ingredient has:

  • Mebicar IC;
  • Mebicar Tathhimfarm;
  • Tranquilar IC.

In the same anatomical-therapeutic-chemical group as Adaptol are:

  • Alprazolam;
  • Amizil;
  • Gidazepam;
  • Grandaxin;
  • Sibazon;
  • Elenium.

Pharmacological action of Adaptol

Adaptol has a moderate tranquilizing (anxiolytic) effect. Reduces or completely eliminates anxiety, restlessness, irritability, psycho-emotional stress and fear. Improves cognitive function, mental performance and attention. Does not stimulate the symptoms of productive psychopathological disorders - delirium and pathological emotional activity.

The drug belongs to daytime tranquilizers due to the fact that its activity does not lead to muscle relaxation and impaired coordination of movements.

Adaptol, according to reviews, does not have a hypnotic effect, but is able to enhance the effect of other hypnotics and reduce insomnia.

The drug has antioxidant activity and works as an adaptogen, membrane stabilizer and cerebroprotector in oxidative stress of various origins.

There is a dopamine-positive component in the neurotransmitter action profile. Antagonistic activity is manifested in relation to the excitation of the glutamatergic and adrenergic systems. The drug enhances the functioning of inhibitory serotonin and GABAergic mechanisms of the brain. This is due to its normosthenic properties.

Adaptol, according to doctors, is able to alleviate nicotine withdrawal.

Bioavailability when taken orally is 80%. Up to 40% of the drug binds to erythrocytes, and 60% is contained in the plasma in a free form. Due to this, Adaptol freely penetrates through the membranes, freely spreading in the body. The maximum concentration of the drug in the blood plasma is reached after half an hour. The high level persists for 3-4 hours, and then gradually decreases. Tetrais completely excreted from the body with urine per day, is not metabolized and is not subjected to biochemical effects in the body.

Indications for use Adaptol

Indications for the appointment of Adaptol are:

  • Neuroses and neurosis-like symptoms (irritability, emotional instability, anxiety, fear);
  • Cardialgia of various origins (not associated with coronary heart disease);
  • Oxidative stress of various etiologies (as an adaptogen and cerebroprotector);
  • Nicotine withdrawal (as part of complex treatment to reduce the craving for smoking);
  • Severe vegetative manifestations in PMS and menopause in women;
  • Poisoning or adverse reactions to benzodiazepines;
  • Poisoning or adverse reactions to neuroleptic and antipsychotic drugs.

Contraindications

Hypersensitivity todione. Adaptol, according to the instructions, is contraindicated in children under 10 years of age.

Use during pregnancy and lactation

Clinical observations on the use of Adaptol during pregnancy and lactation are not enough, therefore, it is not recommended to prescribe it to this group of patients.

How to use Adaptol

Inside, 1 tablet (500 mg) 2-3 times a day, regardless of food intake. The maximum daily dose is 10 g, a single dose is 3 g. The duration of the course of treatment is from 2-3 days to several months.

As a drug that reduces the craving for smoking (in complex therapy) - 1-2 tablets (500-1000 mg) 3 times a day for 5-6 weeks.

Side effects of Adaptol

In most cases, Adaptol is well tolerated.

Sometimes the following violations are possible:

  • Cardiovascular system - lowering blood pressure (normalizes independently);
  • Gastrointestinal tract - dyspeptic disorders (you need to reduce the dose);
  • Respiratory system - bronchospasm;
  • Skin and subcutaneous tissue - allergic reactions, itching, rash (it is necessary to cancel the drug);
  • General - weakness, hypothermia (normalizes independently).

special instructions

Adaptol, according to the instructions, should be used with caution in violations of the liver and kidneys, as well as in patients with arterial hypotension. In addition, caution should be observed when driving vehicles, since the use of Adaptol may help lower blood pressure.

Drug interaction with Adaptol

Adaptol is combined with antidepressants, tranquilizers of the benzodiazepine group, hypnotics, neuroleptics and psychostimulants.

Overdose

The toxicity of Adaptol is very low. A typical clinical picture of an overdose has not been identified. Severe poisonings are not registered. Weakness, dizziness, and hypotension may occur.

If an overdose is suspected, symptomatic treatment, including gastric lavage, should be carried out.

Storage conditions for Adaptol

The medicine should be stored out of the reach of children at a temperature of 15-25 ° C. Shelf life - 4 years.

Adaptol (tetramethyltetraazabicyclooctanedione) is an anxiolytic (anti-anxiety) drug. It has a wide range of medical indications and can be used to treat and prevent a number of common psychosomatic pathologies. Well tolerated by patients. Approved for use in pediatric and geriatric practice. Is the so-called. "daytime tranquilizer". It has a moderate sedative activity, eliminates or alleviates the manifestations of anxiety, anxiety, psycho-emotional stress, increased aggressiveness. It does not have a muscle relaxant effect, does not disrupt coordination, does not depress cognitive activity, does not affect physical performance, which allows the drug to be used in any type of activity. Without its own hypnotic effect, the drug potentiates the action of co-administered hypnotic drugs, improving the quality of sleep and reducing the number of unmotivated nocturnal awakenings. Adaptol has a very high toxicity threshold, because in its chemical structure, it is very close to substances formed in the human body as a result of natural metabolic transformations. Pathological predilection does not cause. Removes the body from the influence of the sympathetic nervous system, which allows the use of the drug in the treatment of vegetative dystonia, relief of symptoms of premenstrual syndrome, and chronic fatigue. Euphoria and high spirits does not cause. Adaptol neutralizes the aggressive action of free radicals and allows you to better tolerate oxygen starvation, which makes it possible to use it in case of circulatory disorders in the internal organs and in case of their hypoxic damage.

The "ginseng-like" effect of Adaptol is in demand in situations where it is necessary to support the nervous system in case of violation of internal regulation and increased stress exposure. The drug has a wide therapeutic range: it is used for neuroses accompanied by psycho-emotional instability and irritability, for cardialgia of non-ischemic origin, to improve the tolerability of drugs of other pharmacological groups (benzodiazepine tranquilizers, antipsychotics). Tetrais chemically inert, which allows it to be combined with other drugs. In addition to the mentioned tranquilizers and neuroleptics, these are antidepressants, hypnotics, psychostimulants, nootropics. Another advantage of Adaptol is its effectiveness in eliminating or suppressing the manifestations of nicotine withdrawal. The drug also has a moderate nootropic effect, stimulates cognitive activity (memory, attention, concentration, intellectual activity), without aggravating the symptoms of psychopathological disorders. A decrease in blood pressure or body temperature is not a reason to cancel Adaptol: in the future, these indicators will return to normal on their own. Allergic reactions, in turn, require the suspension of the drug course and the appointment of another drug. Cases of an overdose of Adaptol are not described in the specialized medical literature. The drug can be used in combination with antidepressants, antipsychotics, sedatives and hypnotics.

Pharmacology

Anxiolytic (tranquilizer). Adaptol is similar in chemical structure to the natural metabolites of the body - its molecule consists of two methylated urea fragments that are part of the bicyclic structure.

Adaptol acts on the activity of structures included in the limbic-reticular complex, in particular, on the emotiogenic zones of the hypothalamus, and also has an effect on all 4 major neurotransmitter systems: GABA-, choline-, serotonin- and adrenergic, contributing to their balance and integration, but does not have a peripheral adrenoceptor blocking effect.

Eliminates or reduces anxiety, anxiety, fear, inner emotional tension and irritability. The calming effect is not accompanied by muscle relaxation and impaired coordination of movements.

Does not reduce mental and motor activity, so Adaptol can be used during the working day or study. Does not create an elevated mood, a feeling of euphoria.

It does not have a hypnotic effect, but enhances the effect of hypnotics and improves the course of sleep in case of its disturbances.

Adaptol relieves or relieves nicotine withdrawal.

In addition to the sedative, it has a nootropic effect. Adaptol improves cognitive functions, attention and mental performance without stimulating the symptoms of productive psychopathological disorders - delirium, pathological emotional activity.

Pharmacokinetics

Suction

After oral administration, Adaptol is well absorbed from the gastrointestinal tract (77-80%). Cmax of the active substance in blood plasma is reached 0.5 hours after taking the drug. A high concentration of the active substance persists for 3-4 hours, then gradually decreases.

Distribution

Up to 40% of the dose taken is bound to erythrocytes. The rest does not bind to plasma proteins and is in the blood plasma in a free form, so the active substance is freely distributed throughout the body and freely overcomes cell membranes.

Metabolism

The active substance is not metabolized and does not accumulate in the body.

breeding

About 55-70% of the dose taken is excreted from the body with urine, the rest - with feces unchanged during the day.

Release form

Tablets are white or almost white, round, flat-cylindrical, with a chamfer and a risk mark.

Excipients: methylcellulose - 3.3 mg, calcium stearate - 1.7 mg.

10 pieces. - cellular contour packings (2) - packs of cardboard.

Dosage

The drug should be taken orally, regardless of food intake, 500 mg 2-3 times / day. The maximum single dose is 3 g, the daily dose is 10 g. The duration of the course of treatment is from several days to 2-3 months.

In complex therapy, as a means of reducing the craving for tobacco smoking, 500-1000 mg 3 times / day are prescribed for 5-6 weeks.

Overdose

The drug has low toxicity. There is no typical clinical picture of an overdose. Manifestations of severe poisoning are not registered.

Symptoms: possible weakness, arterial hypotension, dizziness.

Treatment: if an overdose is suspected, gastric lavage and symptomatic therapy should be carried out.

Interaction

Perhaps the simultaneous use of Adaptol with neuroleptics, tranquilizers (including benzodiazepines), hypnotics, antidepressants and psychostimulants.

Side effects

Rare: dizziness, lowering blood pressure, dyspeptic disorders, allergic reactions (skin rash, itching).

When used in high doses: bronchospasm, lowering body temperature, weakness.

Indications

  • neuroses and neurosis-like states (irritability, emotional instability, anxiety and fear);
  • to improve the tolerance of antipsychotics and tranquilizers in order to eliminate the somatovegetative and neurological side effects caused by them;
  • cardialgia of various origins (not associated with coronary artery disease);
  • nicotine withdrawal (as part of complex therapy as a means of reducing craving for tobacco smoking).

Contraindications

  • pregnancy;
  • lactation period (breastfeeding);
  • hypersensitivity to the components of the drug.

Application features

Use during pregnancy and lactation

The use of the drug during pregnancy and lactation (breastfeeding) is contraindicated.

special instructions

With a decrease in blood pressure and / or body temperature (possibly by 1-1.5 ° C), the drug should not be stopped. Blood pressure and body temperature normalize on their own.

If allergic reactions occur, the drug should be discontinued.

Addiction, dependence (mental and physical) and withdrawal syndrome with the use of the drug Adaptol have not been established.

Influence on the ability to drive vehicles and control mechanisms

The drug can cause a decrease in blood pressure and weakness, which can adversely affect the ability to drive vehicles and work with mechanisms. Caution should be exercised when used in patients engaged in potentially hazardous activities.

This product contains an active ingredient mebicar , additional components: methylcellulose, calcium stearate.

Release form

The drug is available in the form of tablets of 500 mg, 300 mg. They are white in color, flat-cylindrical in shape, there is a risk and a chamfer on the tablet. In a cardboard box - two packs of 10 tablets.

pharmachologic effect

Adaptol- This is a medicine belonging to the group of anxiolytic drugs. The drug has a tranquilizing effect. Effectively removes the feeling of fear, anxiety, eliminates irritability, anxiety, reduces strong emotional stress. The influence of this drug is not accompanied by changes in motor functions and muscle relaxation, a decrease in mental activity. Thus, the remedy is considered a daytime tranquilizer.

Adaptol tablets do not have a hypnotic effect, but at the same time it potentiates the effect of drugs that are used for treatment.

The drug provides an antioxidant effect, which is especially clearly manifested under stress of various origins, accompanied by oxidative phenomena.

The drug has the properties of an antagonist-agonist of the adrenergic system. It is noted that the drug has a positive effect as a neuromodulator, in connection with which a normosthenic effect is noted.

When taking pills, the severity of withdrawal symptoms in people who have stopped smoking tobacco is reduced.

The active substance affects the emotiogenic zones of the hypothalamus and the four main neurotransmitter systems, ensuring their balance and integration. At the same time, there is no adrenoblocking peripheral effect.

The nootropic effect of the drug is also noted. Adaptol activates cognitive functions, improves mental activity and attention.

Pharmacokinetics and pharmacodynamics

The level of bioavailability is 80%. Once in the blood, the active substance is bound (40% of the dose received), the rest of it in the plasma is in a free form. The highest concentration in the blood is observed 0.2 hours after oral administration, the same concentration is noted for 3-4 hours, after which the concentration begins to gradually decrease. Excreted by the kidneys (most) and intestines. It does not accumulate in the body.

Indications for use Adaptol

The following indications for the use of Adaptol are determined:

  • and neurosis-like symptoms;
  • complex treatment, if necessary, to stop the somatovegetative side effects of antipsychotics and improve the tolerability of drugs from this group;
  • pain in the heart, not associated with seizures;
  • vegetative manifestations with;
  • oxidative stress of various origins;
  • complex therapy of dependence on nicotine.

You can learn more about when Adaptol tablets are prescribed, what they are for, you can ask your doctor.

Contraindications

Wikipedia indicates that a contraindication for taking the medicine is to the components of Adaptol.

Side effects

Side effects in the treatment of Adaptol in patients are rare. Sometimes allergic manifestations are observed. When using high doses of the drug, the patient may experience dyspeptic disorders. In this case, the treatment is suspended. In very rare cases, hypotension and may occur. As a rule, these phenomena pass independently.

Instructions for Adaptol (Method and dosage)

The instruction for Adaptol provides that the tablets can be taken regardless of the meal period. As a rule, patients are prescribed from 300 mg to 500 mg of the drug 2-3 times a day. The drug is prescribed for a period of 2 days to 3 months, depending on the diagnosis and the characteristics of the course of the disease. Instructions for the use of Adaptol indicate that the maximum allowable single dose of the drug is 3 g, its maximum dose per day is 10 g. In the treatment of nicotine addiction, the drug is prescribed at a dose of 0.6-0.9 g three times a day.

Instructions for use Adaptol children

For children, the drug is prescribed from the age of ten. Children are prescribed at a dose of 300-500 mg three times a day. The treating specialist will tell you in detail about the features of the treatment.

Overdose

This drug has low toxicity. Therefore, with an overdose of the drug, a typical picture of an overdose is noted. When taking very large doses, the drug may be noted hypotension , .

If there is a suspicion of an overdose of Adaptol, symptomatic therapy is practiced, and gastric lavage is also performed.

Interaction

You can simultaneously take Adaptol and tranquilizers, antipsychotics, sleeping pills, psychostimulants, antidepressants.

Terms of sale

It is sold in pharmacies by prescription.

Storage conditions

It is necessary to protect from children, store at a temperature of 15-25 ° C.

Best before date

special instructions

The patient does not develop addiction to the drug, there is no withdrawal syndrome. During treatment, you can drive vehicles and perform activities that require increased attention. However, you need to be careful.

If the body temperature decreases during therapy, it is not necessary to stop treatment. Gradually, the temperature and blood pressure are normalized. If they occur, you need to stop treatment.

Analogues of Adaptol

Coincidence in the ATX code of the 4th level:

The drugs seem to work on the body Mebix , Mebikar-Tatchimpharm etc. The price of Adaptol analogs depends on their dosage and manufacturer, some drugs have a lower cost.

Which is better - Adaptol or Grandaxin?

- This is a drug that belongs to the group of benzodiazepine derivatives and has an anxiolytic effect on the body, while not having a sedative, anticonvulsant effect. In general, its effect on the body is similar to the effect that Adaptol has. Which drug to prefer, the doctor will tell you individually.

children

It is not used for the treatment of children under the age of ten.

With alcohol

When discussing drug compatibility with alcohol, it should be noted that Adaptol and alcohol should not be combined, since when they are taken together, headaches and a pronounced drop in blood pressure may occur. More serious side effects are possible, so do not drink alcohol while taking this drug.

During pregnancy and lactation

The active ingredient of the drug easily enters all tissues of the body. There are no clear results of clinical studies of the effect of Adaptol on expectant mothers and. Therefore, it is not recommended to use this tool in this case.

Produced in tablets, it belongs to tranquilizers, its action is aimed at relieving pain symptoms and anxiety, relief, mental stress, unreasonable fears, pathological irritability.

At the heart of the drug tetra(in other words, mebicar), a chemical compound acts similarly to a natural metabolite in the human body.

The active component dulls the intensity of the activity of the part of the brain responsible for the emotional background.

Advantages and disadvantages of the drug

Adaptol affects the human brain activity quite gently, does not cause side effects common among other analogues, such as impaired coordination, weakening of muscle tone, dulling of the reaction or euphoria.

The drug is well suited for patients with cravings for smoking, used during menopause or oxidative stress. Medicine fast spreads throughout the body (the primary effect can be observed after 15-20 minutes), the duration of the achieved effect lasts up to 3-4 hours - the patient feels peace and tranquility. Stress will no longer bother the patient. The drug does not have a toxic effect on the liver and is excreted by the kidneys from the body.

Adaptol is not addictive, patients do not have a withdrawal syndrome. When taking the drug, there are no contraindications for driving vehicles and mechanisms, performing work that requires increased attention.

A slight tranquilizing effect, prevents the occurrence of convulsions, prevents impaired motor functions and loss of orientation in space. In general, the effect of taking the drug is the correction and stabilization of mood, the clarification of thinking, and the increase in productivity.

The disadvantages of Adaptol include its price (the average cost in Russia fluctuates around 750 rubles), for many analogues it is cheaper. Taking the medicine cannot be combined with alcoholic beverages, so you will have to be away from entertainment during the treatment.

Drug analogues

Like any other drugs, Adaptol has a number of analogues worthy of attention, this is the name of medicines that, according to their pharmacological indications for use, are similar to the required drug.

Among analog products, you can always choose a less advertised, but effective medicine, with a lower cost and good reviews. The price, as a rule, includes the budget for advertising, organized work to promote the brand on the market. Is it worth paying for it?

So, first of all, it is worth considering the structural analogues of Adaptol, determined by the content of the main active substance, it is worth highlighting the following:

  • Mebikar (Ukraine);
  • Mebikar-Tatchimpharm (Russia);
  • Mebiks (Russia);
  • Tranquilar (Ukraine).

There are other substitutes for Adaptol, each of which has its own characteristics, we will briefly consider the most popular:

Cheap domestic analogues

Price matters in modern life, everyone wants to cut costs, especially when it comes to treatment. Sometimes, the cost of the prescribed course goes beyond the financial capabilities of the patient.

In such cases, it is worth taking a closer look at more affordable domestic drugs (mainly Russian and Ukrainian) of a similar effect, since cheap Adaptol analogues are present on the market in large quantities:

OTC Options

Adaptol belongs to antidepressants, and it is quite natural that it is sold exclusively by prescription, however, you can also find over-the-counter drugs similar in effect in a pharmacy:

  • Mebicar IC;
  • Selank;
  • Tranquilar IC.

However, you should not self-medicate, or independently replace the drug prescribed by the doctor, even if it is found on the free market - only the doctor professionally compares the patient's problem and contraindications to taking the remedy.

Comparative characteristics

We tried to impartially compare Adaptol and its popular counterparts in order to find out which is better in each case.

The advantage of Adaptol is its good compatibility with other medications (tranquilizers, neuroleptics, psychostimulants, antidepressants). The only strict contraindication when taking the medication is that it is strictly forbidden to use it together with alcohol.